fusin

fusin
Lymphocyte surface protein originally described as being an essential cofactor for HIV bound to CD4 to fuse with and enter the cell, later shown to be a chemokine receptor (CXCR4 in the case of lymphotropic virus strains, CCR5 for myelotropic strains). Since FIV will infect CD4-cells it is possible that the chemokine receptor is the original binding site and CD4 the co-receptor, rather than the converse.

Dictionary of molecular biology. 2004.

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Look at other dictionaries:

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  • Fusin — geographical name see Fuxin …   New Collegiate Dictionary

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  • fusin — A G protein–linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + in] …   Medical dictionary

  • fusin — North Country (Newcastle) Words nourishment, abundance …   English dialects glossary

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  • Fusin — /fooh sin /, n. Older Spelling. Fuxin …   Useful english dictionary

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  • LESTR — CXCR4 Größe 352 AS; 39,7 kDa Struktur 7TM Bezeichner …   Deutsch Wikipedia

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